Thank you for your question. I look forward to working with you to provide you the information you are seeking for educational purposes only.
Your friend does not have many options I am afraid. If she is out of status because she separated and did not attend the interview, she must leave the US if she does not find some sponsor for a different type of visa. If she stays and is caught, in light of the US Supreme Court striking down the President's executive order, then she would face up to a 10 year ban if caught.
So, she can apply to colleges or schools to seek to teach and get some type of work visa. Other than that, if she is seeking a visa as an artist she would have to prove she is famous and an expert in her area of art to satisfy those requirements. Quite honestly, looking for employment or enrolling in a PhD program would be her best chances of being able to remain in the US.
Thank you for your reply.
If she gets a sponsor, she can file for change of status, but if she does not have one and her visa is currently expired now she needs to leave, because immigration WILL check to see if she has overstayed before.